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(solution) A 32-year-old man is recovering from third degree burns over 50%


 A 32-year-old man is recovering from third degree burns over 50% of his body surfacearea. His serum potassium level is low (2.9 mEq/L), which is common in healing burnvictims. He exhibits postural hypotension (i.e., blood pressure falls on standing) andskeletal muscle weakness. If the equilibrium potential for K+ in a neuron is -105 mVand the equilibrium potential for Na+ is +55 mV, what would be an approximate valuefor the resting membrane potential for a neuron in this man?A. +22 mVB. +52 mVC. +80 mVD. -25 mVE. -50 mVF. -98 mV


How would this value of the resting membrane potential explain skeletal muscle weakness? 


Solution

 

From Nernst equation, Veq={RT/zF}ln{[X]out/[X]in}

 

=(8.314 x 310)/(96485 x 2)ln{2.9/135}*1000mV/V

 

=-51.2mV thus it is about -52mV

 

R=gas constant

 

T= body temperature in kelvin

 

Z total...

 


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Sep 13, 2020

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